What is Non-Invasive Prenatal Testing?
North Surrey Midwives offer both Harmony and Panorama tests which analyse fetal DNA found in a woman’s bloodstream when she is pregnant. Both tests assess the risk of the fetus having any of the three most common Trisomy conditions: Downs Syndrome, Patau Syndrome and Edwards Syndrome (Trisomy 21, 18 and 13). Sex chromosome anomalies including Turner and Klinefelter syndrome can also be assessed, and Panorama can also check for Triploidy and Microdeletions.
What does the screening involve?
The Harmony or Panorama test will be performed in your own home by an experienced midwife, taking 30-45 minutes. Two vials of blood will be taken from your arm. These samples will then be sent tracked next day delivery to our laboratory who will analyse the blood for fetal DNA.
How accurate are the Harmony and Panorama screening tests?
With a >99% accuracy, the Harmony and Panorama tests are far more accurate than conventional screening currently offered on the NHS, which only detects 70-80% of fetuses with Downs syndrome. They are still screening tests and do not replace invasive diagnostics (with the risk of miscarriage), so if your result comes back as high risk you may still need to have invasive testing should you choose to.
What is the difference between the Harmony and Panorama tests?
This table compares the Harmony and Panorama tests. For more detailed information on the additional Microdeletions which Panorama can check for please click here.
|Available after 10 weeks
||Available after 9 weeks
||£345+mileage (basic panel)
|Processed in UK
||Processed in USA
|›99% T21 (Down’s Syndrome)
||›99% T21 (Down’s Syndrome)
|›97.4% T18 (Edwards Syndrome)
||›98.2% T18 (Edwards Syndrome)
|>93.8% T13 (Patau’s Syndrome)
||›99% T13 (Patau’s Syndrome)
|Optional analysis of sex chromosome (x,y) conditions
||Optional analysis of sex chromosome (x,y) conditions
|Optional fetal gender determination >99.9%
||Optional fetal gender determination >99.9%
|Results in 3-5 business days
||Results in 6-9 business days
|Redraw rate of 3%
||Redraw rate of 4%
|Less than 0.1% false positive rate
||Less than 0.1% false positive rate
||Optional analysis of micro deletions at cost of £150
|Also available in twin, multiples, singleton donor. Twin sensitivity is similar to singleton pregnancies. For T21 – 99%
||Not available for vanishing twin, multiple gestation of more than 2 fetuses, or twins conceived using an egg donor or surrogate.
Who is eligible to have the Harmony test?
See the table above for eligibility for each of the tests or contact us for more information. Please note you need to have a scan prior to NIPT screening, either from the NHS or privately, in order to date the pregnancy and determine the number of fetuses in utero.
Can the Harmony and Panorama tests tell me the gender of my baby?
Yes, and this is included at no extra cost.
Our package includes:
- A telephone consultation to explain the procedure and explore your options (if required)
- A home visit to carry out the screening
- Confirmation of gender at no additional cost
- A follow-up telephone call to discuss the results, including counselling on your options if a high risk result is returned
- PLEASE NOTE: you will need to have had a scan (private or NHS) before we can undertake NIPT screening, to determine gestational age and whether you are having twins/multiples
How much does NIPT cost?
Our fee for Harmony testing is £365 (plus 45p a mile if outside local area).
Panorama fees are as follows:
Basic panel £345+mileage – chromosomes 13, 18, 21, X & Y; Triploidy
Basic plus panel £375+mileage – chromosomes 13, 18, 21, X & Y; Triploidy; 22q11.2 deletion
Extended panel £495+mileage – chromosomes 13, 18, 21, X & Y; Triploidy; 22q11.2 deletion + four microdeletions
(note: the extended panel takes 7-10 working days to receive a result)
What areas do you cover?
We will travel up to 45 minutes from our practice in Walton on Thames, including (but not limited to): Esher, Shepperton, Weybridge, Cobham, Chertsey, Woking, Camberley, Epsom, Guildford, Godalming, Farnham, Dorking, Reigate, Redhill, Kingston, Surbiton, Richmond, Wimbledon, Twickenham, Windsor, Ascot, Bracknell. Please enquire to find out if we cover your area.